the Centre for Applied Bioscience Research’s Equipment Spotlight – Tewitro® TW 24 (manufactured by Courage + Khazaka electronic GmbH)

the Centre for Applied Bioscience Research possesses the Tewitro® TW 24 instrument, a state-of-the-art permeability testing equipment (funded by Enterprise Ireland), available at the Centre for Applied Bioscience Research for industry collaborations.

This equipment is applied in many sectors, including dermatology, cosmetics, and pharmaceuticals, and helps in evaluating the efficacy and safety of topical products. It is particularly useful for individuals working in roles such as product development, safety testing, and quality control.

Some of the ways the Centre for Applied Bioscience Research can use this equipment include: 

• Assessing how easily substances penetrate the skin (which is crucial for the development of effective and safe topical products)
• Measuring the impact of products on skin barrier function to ensure they perform as intended
• Using skin tissue models to extend safety evaluations without relying on animal or human volunteer testing
• Ensuring the reliability and consistency of tissue cultures used in testing
• Using a variety of probe configurations to match specific experimental needs and well plate sizes

Key advantages of the Tewitro® TW 24 instrument include (but are not limited to):

• Tewitro® TW 24 can be used in 24-well plates (6×4)
• TW 24 is the only device to measure the water evaporation from cultured tissue sets (wells in a plate with medium) in up to 24 wells simultaneously
• The Tewitro® is well-suited to non-invasively monitor TEWL (transepidermal water loss) of cultured skin tissue samples

If you would like to learn more about this instrument and how the Centre for Applied Bioscience Research utilizes it, or if you’re interested in collaborating with the Centre for Applied Bioscience Research, please contact Damian Gornik, the Centre for Applied Bioscience Research’s Communications Officer, via email ✉️ damian.gornik@mtu.ie