Mariana Juca da Silveira e Silva (Bioengineering Organ-on-Chip Research Group (OOC) at CABR) – Research Work Spotlight

Recently, Mariana Juca da Silveira e Silva, a PhD researcher in the Bioengineering Organ-on-Chip Research Group (OOC) at CABR, worked on antibiofilm assays, which are laboratory tests used to assess the ability of a substance to inhibit or disrupt bacterial biofilms.

Bacterial biofilms are protective layers formed by clusters of bacteria, significantly increasing their ability to survive, adapt, and resist treatment.

Antibiofilm assays are essential for the early screening of antimicrobial agents targeting these biofilm-associated pathogens. These pathogens contribute to a range of life-threatening infections in humans and often exhibit high resistance to conventional therapies.

The assay performed by Mariana Juca da Silveira e Silva (CABR) enables researchers to quantify biofilm levels and evaluate how effectively a compound can prevent or disrupt biofilm formation. This provides valuable insights for the development of more effective antimicrobial treatments.